IOZK - Immun-Onkologisches Zentrum Köln
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Dr. Wilfried Stücker


Tumour Immunology
Pharmaceutical Biology
Tumour Immunology
Naturopathic Practitioner

"With our multi-disciplinary approach at the IOZK we offer our patients valuable treatment options which supplement and complement conventional methods."

The insights we have gained in the last decades about the functioning of the immune system play an important role in our work as team of experts. Given the wealth of medical knowledge in today's world it is essential to collaborate in interdisciplinary networks and to exploit synergies in this way. 

This is also the guiding principle of our team at the IOZK. The close cooperation between our medical and scientific experts provides our patients with valuable treatment benefits derived from cutting-edge research and knowledge. This has resulted in our team developing the first therapeutic autologous polyspecific tumour vaccine in Europe (based on dendritic cells loaded with virus-infected autologous tumour antigens), produced under the regulations laid out by the Medicines Act.


Prof. Dr. Volker Schirrmacher


Tumour Immunology - Head of Research

"Through the specific activation and individual support of the immune system to fight against a patient’s own cancer, new and promising treatment options are available to patients today."

Overcoming barriers is one of the current challenges in oncology. Only then can we develop innovative therapies.Immunotherapy is such an example of a new treatment in oncology. Successful results have shown us that we are on the right path with our treatment approach.

At the IOZK we offer patient-specific immunotherapy. We are flexible and can adapt quickly to the needs of our patients. This way we can implement individual therapy much better and in a more personal manner than, for example, at a university clinic. We work to the basis of clinical studies that are specifically optimised for the individual patient.



Stefaan Van Gool MD PhD



Specialist in Paediatric Hemato Oncology
Medical Management of Translational Oncology
Qualfied Person (German Medicines Act)
Responsible Medical Person (German Medicines Act)

"The manufacturing authorisation now enables us to make this treatment available to our patients more readily. Through this, they have the chance of a longer life with a better quality of life."

Currently oncolytic viruses combined with a dendritic cell vaccine are approved for the treatment of patients with cancer at the IOZK. At the same time, new developments in preclinical research can easily be translated into clinical applications through the interdisciplinary IOZK team.


Selected publications of Prof. Dr. Van Gool 






Dr. med. Katharina Sprenger


Immune Oncology

Specialist in General Medicine 
Qualfied Person (German Medicines Act)

"When treating tumour diseases, it is becoming ever more apparent that there is not “the patient” and “the tumour”. Standardised procedures, which do not take the individual situation into consideration, are only of limited benefit."

It is my belief that the future of tumour therapy lies in personalised medicine. The guidance and strengthening of the patient’s own defence mechanisms – instead of exclusively destroying the tumour through surgery, chemo- and radiation therapy – convinces me. I am delighted that I have the good fortune to be able to work on the development of such strategies to benefit the patient.


Dr. med. Tobias Sprenger


Specialist in General Medicine
Consultant for Expert Medical Opinions

"Guidelines should support doctors and patients to find the correct therapy, not replace the thinking process."

In my profession as a doctor it is of utmost concern to me to understand the values and concerns of my patients. It is important to me to recognise them as individuals and support their autonomy. Individuals who consciously select their own mode of therapy and identify with it stand a better chance of mastering a health crisis than those that blindly leave the treatment decision to somebody else. This is the reason why I do not trust medical practice which blindly follows rules and regulations without acknowledging the individual patient.